Scrum is designed so developers can work 40 hour weeks. No more death marches. If we are now burning through good product owners, we have just shifted the constraint.Scrum does not detail the product owner's relationship with the world outside the team. If one person cannot stay on top of all the details, presumably that individual is part of a marketing organization that can. Like all good developers, Scrum only defines the product owner / team interface. What happens on the enterprise side of that interface is someone else's problem.
Nice thoughts on Scrum' role that it plays in making a world with less burn-out (if it ever does).